Macropen 400mg №16 pills


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Macropen 400mg №16 pills

Macropen is an antibiotic from the group of macrolides, the active ingredient is midecamycin. Spectrum of action: gram-positive microorganisms, intracellular pathogens and gram-negative microorganisms. Macrolide, has a bacteriostatic action in low doses, in large doses - bactericidal.

Special features

Drug interactions
Caution should be exercised while using warfarin, because midekamitsin can slow its removal, which increases the risk of hemorrhage.

Pharmaceutical action

Rendersantibacterial action. Active against Gram-positive bacteria (Staphylococcus, Streptococcus, Pneumococci, Bacillus anthracis, Corynebacterium diphtheriae, Listeria ispsov isp .) and other bacteria, such as mycoplasma, ureaplasma, chlamydia and legionella.


- hypersensitivity to the active substance or auxiliary components of the drug
- severe liver failure
- children's age up to 6 years.

special instructions

With prolonged therapy, liver enzyme activity should be monitored, especially in patients with impaired liver function.
As with the use of any other antimicrobial drugs, long-term treatment can lead to excessive growth of resistant bacteria. Prolonged diarrhea may indicate the development of pseudomembranous colitis.
Pregnancy and lactation
Use of the drug during pregnancy is indicated only in cases where the potential benefit to the mother exceeds the risk to the fetus.
Nursing mothers should stop breastfeeding during treatment with Macropen, as the drug is excreted into breast milk.
Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous machinery.
Not reported on the effect of Macropene on the psycho-physiological reactions and ability to drive a car and other mechanisms.

Precautionary measures

Side effects
Decreased appetite, stomatitis, nausea, vomiting and diarrhea. Allergic reactions (skin rash, urticaria, pruritus, eosinophilia), increased transaminase activity and jaundice are also possible.

It is a drug.Consultation with a doctor is required.


One tablet contains:
active ingredient - midekamycin 421.0 mg

Mode of application

Before meals. Adults and children weighing more than 30 kg: one tablet 400 mg 3 times a day. The maximum daily dose of midecamycin for adults is 1600 mg.
The duration of treatment is from 7 to 14 days. Chlamydial infections need to be treated for 14 days.