Pancef 400mg №10 pills

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Pancef 400mg №10 pills

pills, covered with a white or almost white film coating, oblong shape. In a carton box a bottle of dark glass with 10 tab.

Special features

At the same time taking Pantsef with other potentially nephrotoxic drugs, the negative effects on the kidneys can be increased.

Pharmaceutical action

Semisynthetic cephalosporin antibiotic III generation, which has a wide spectrum of action. Bactericidal effect. Cefixime inhibits the synthesis of the cell membrane of the fungus. Thereby causing its death .. Cefixime is resistant to the action of β-lactamase produced by most gram-positive and gram-negative bacteria.
Active against gram-positive bacteria: Streptococcus pneumoniae, Streptococcus pyogenes; Gram-negative bacteria: Haemophilus influenzae, Moraxella (Branhamella) catarrhalis, Escherichia coli, Proteus mirabilis, Neisseria gonorrhoeae.

Contraindications

The drug is not taken with: hypersensitivity to the components; children under 12 years of age, pregnancy, breastfeeding, renal insufficiency and bronchial asthma.
With caution in: diseases of the digestive system (including h. Colitis, enteritis and ulcerative colitis in history with therapy with cephalosporins), liver failure; chronic alcoholism, tendencies to the development of bleeding.

special instructions

With prolonged use, there may be a violation of the normal intestinal microflora, which can cause the development of diarrhea and pseudomembranous colitis.
During treatment, a positive direct Coombs reaction and a false-positive reaction of urine to glucose are possible.
With an increase in the recommended dose of the drug, an overdose occurs, signs of which are: dizziness, vomiting and diarrhea.
In such a situation it is necessary: ​​wash the stomach and take an enterosorbent agent, but no later than 2 hours after taking the drug. Further symptomatic therapy is carried out.



It is a pharmaceutical drug. Use only as directed by your doctor.

Composition

1 tab. contains: the main substance cefixime 400 mg and auxiliary - microcrystalline cellulose; calcium hydrogen phosphate dihydrate; gelatin; sodium lauryl sulfate; magnesia stearate; hypromellose; macrogol 4000; titanium dioxide.

Mode of application

pills are taken orally.The tablet is swallowed whole, it can not be crushed and chewed. The drug can be taken before, during or after a meal, washed down with a small amount of water. The daily dose of the drug is taken as a reception or divided into 2 doses with an interval of 12 hours. The course of treatment and the dose of the drug are determined individually, depending on the disease and the patient.
Recommended doses:
In inflammatory diseases of the respiratory tract, upper respiratory tract, organs of the urinary system, 400 mg per day.
For uncomplicated gonorrhea, a single dose of 400 mg.
In patients with impaired renal function (with CK from 21 to 60 ml / min) or on hemodialysis, the daily dose is reduced by 25%; in patients with CK≤20 ml / min or on peritoneal hemodialysis, the daily dose is reduced by 2 times.