Paracetamol candles 500mg №10
Composition1 suppository contains paracetamol - 500 mg
pharmachologic effectParacetamol is a non-narcotic analgesic. It has analgesic, antipyretic and minor anti-inflammatory effects. The mechanism of action is associated with inhibition of prostaglandin synthesis, a predominant effect on the center of thermoregulation in the hypothalamus.
IndicationsPain syndrome of low and moderate intensity of various genesis (including headache, migraine, toothache, neuralgia, myalgia, algomenorrhea; pain with injuries, burns). Increased body temperature for colds and other infectious and inflammatory diseases.
ContraindicationsHypersensitivity to paracetamol. Pronounced dysfunction of the liver or kidneys. Genetic absence of glucose-6-phosphate dehydrogenase. Blood disorders. Undesirable use during pregnancy and lactation. Be wary of Gilbert's syndrome (constitutional hyperbilirubinemia). Chronic active alcoholism.
Dosage and administrationRectal in adults and adolescents weighing more than 60 kg is used in a single dose of 500 mg.
Side effectsAt therapeutic doses, the drug is usually well tolerated.
On the part of the digestive system: possible nausea, abdominal pain; rarely with prolonged use - abnormal liver function.
Allergic reactions: skin rash, urticaria, angioedema are possible.
On the part of the urinary system: rarely with prolonged use - renal dysfunction.
On the part of the blood system: rarely with prolonged use - anemia, agranulocytosis, thrombocytopenia.
If you experience adverse reactions, you must stop taking the drug and consult a doctor.
special instructionsIt is used with caution in patients with impaired liver or kidney function. The risk of hepatotoxic action increases with the simultaneous appointment of barbiturates, difenina, carbamazepine, rifampicin, zidovudine, and other inducers of microsomal liver enzymes. In order to avoid toxic damage to the liver, paracetamol should not be combined with the intake of alcoholic beverages, as well as be taken by persons prone to chronic alcohol consumption.
OverdoseSymptoms: pallor of the skin, anorexia, nausea, vomiting, hepatonecrosis (the severity of necrosis directly depends on the degree of overdose).
Treatment: gastric lavage, activated carbon.
Storage conditionsStore in a dark place, out of reach of children.
It is a pharmaceutical drug. Use only as directed by your doctor.
Attention! During storage must comply with the temperature regime.