Picamilon 50mg №30 pills

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Picamilon 50mg №30 pills

pills are white or white with a faint creamy tint color, flat-cylindrical, with a bevel.


1 tab.
N-nicotinoyl-gamma-aminobutyric acid sodium salt 20 mg

Excipients:

potato starch, magnesium hydroxycarbonate hydrate (basic magnesium carbonate), sucrose, calcium stearate or stearic acid, talc.
30 pieces - banks of dark glass (1) - packs cardboard.

Clinico-pharmacological group:

Nootropic drug

Pharmaco-therapeutic group:

Nootropic agent

pharmachologic effect

Nootropic agent, dilates the blood vessels of the brain. It also has a tranquilizing, psychostimulant, antiplatelet and antioxidant effects. Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral circulation (increases the volumetric and linear speed of cerebral blood flow, reduces the resistance of cerebral vessels, suppresses platelet aggregation, improves microcirculation).

In exchange admission increases physical and mental performance, reduces headache, improves memory, normalizes sleep; helps to reduce or eliminate feelings of anxiety, tension, fear; improves the condition of patients with motor and speech disorders.

Pharmacokinetics

Absorption is fast and complete, regardless of the route of administration. It penetrates the BBB and is retained for a long time in the tissues of the body. Bioavailability - 50-88%. Excreted mainly by the kidneys in unchanged form. T1/2- 0.51 hour

Indications

Cerebrovascular insufficiency, asthenia, depressive disorders in old age.
Conditions accompanied by anxiety, fear, increased irritability, emotional lability. Asthenic conditions caused by various neuropsychiatric diseases.

In the complex treatment - for the relief of acute alcohol intoxication; in chronic alcoholism - to reduce asthenic, asthenoneurotic, postpsychotic, pre-relapse states, as well as alcoholic encephalopathy.
As part of complex therapy - migraine (prevention), TBI, neuroinfection.

Improving the tolerance of physical and mental stress (for people in tense and extreme conditions of activity; to restore physical performance of athletes, to increase resistance to physical and mental stress).

Open-angle glaucoma (to stabilize the visual function).
In urological practice (in children older than 3 years and in adults with urinary disorders) to improve the adaptive function of the bladder (reduction of detrusor hypoxia).

Dosing regimen

Is ingested, regardless of the meal.
With cerebrovascular diseases a single dose - 20-50 mg 2-3 times / day, daily dose - 60-150 mg. The course of treatment is 1-2 months. Repeated course - in 5-6 months.
Depressive states of late age: 40–200 mg / day for 2–3 doses, the optimal dose range is 60–120 mg / day for 1.5–3 months. As an antiastenic and anxiolytic - 40-80 mg / day, if necessary, up to 200-300 mg / day, for 1-1.5 months.
In case of alcoholism during the period of withdrawal, a dose of 100-150 mg / day is prescribed, a short course of 6-7 days; with more persistent violations beyond withdrawal - 40-60 mg / day for 4-5 weeks.
For recovery and at increased loads - 60-80 mg / day for 1-1.5 months, for athletes in the same dose, for 2 weeks. training period.
Parenterally administered in / in drip or jet (slowly), in / m.
In chronic cerebrovascular accidents - in / in or in / m, 100-200 mg, 1-2 times / day, daily dose - 20-40 mg. Depending on the patient's condition, they are used in the morning in / in the drip, in the evening - in / m; or within 10 days in / in, then in / m. The course of treatment is 15-30 days.
To relieve acute uncomplicated intoxication with ethanol, the complex therapy is administered in a saturating dose of 5 mg / kg and supporting — 1.56 mg / kg / h in a volume of 2.5 l of an infusion solution, for 4 hours, in the morning and evening.
In asthenic conditions, depending on the severity of the disease, in addition to oral administration, intramuscularly injected in a daily dose of 20-40 mg for 1 month

Side effect

From the side of the central nervous system: irritability, agitation, anxiety, dizziness, headache.
Allergic reactions: skin rash, itching.
Other: nausea.

Contraindications

Chronic renal failure, pregnancy, lactation, hypersensitivity to nicotinoyl gamma-aminobutyric acid.

Use during pregnancy and lactation

Contraindicated use during pregnancy, during lactation (breastfeeding).

Application for violations of kidney function

Contraindicated in chronic renal failure.

Drug interaction

Reduces the duration of the action of barbiturates.
Enhances the effect of narcotic analgesics.



It is a pharmaceutical drug. Use only as directed by your doctor.