Ventolin 100mcg / dose 200dos aerosol for inhalation

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Ventolin 100mcg / dose 200dos aerosol for inhalation

pharmachologic effect

Salbutamol is a selective agonist of b2-adrenoreceptors. In therapeutic doses, it acts on the b2-adrenoreceptors of the smooth muscles of the bronchi, having little or no effect on the b1-adrenoreceptors of the myocardium.

Indications

Bronchial asthma
- relief of attacks of bronchial asthma, including the exacerbation of severe asthma;
- prevention of attacks of bronchospasm associated with exposure to an allergen or caused by exercise;
- use as one of the components for long-term maintenance therapy of asthma.
Chronic obstructive pulmonary disease (COPD), accompanied by reversible airway obstruction, including chronic bronchitis and pulmonary emphysema.

Contraindications

- Hypersensitivity to any component of the drug.
- Conducting preterm labor.
- Threatening abortion.
- Children's age up to 2 years.

Use during pregnancy and lactation

During pregnancy and lactation, the drug is prescribed only in cases where the expected benefit to the mother outweighs any possible risk to the fetus.
Salbutamol is likely to penetrate into breast milk, so nursing women are not recommended to take it, except in cases where the expected benefit to the mother outweighs any potential risk to the baby. It is not known whether salbutamol present in breast milk has any negative effect on a newborn baby.

Side effects

Salbutamol can cause mild tremor of skeletal muscles, which is usually most pronounced in the hands and is a characteristic side effect of all b2-adrenoreceptor agonists. Occasionally, patients have headache, dilated peripheral vessels and a slight compensatory increase in heart rate. Very rarely, hypersensitivity reactions (including angioedema, urticaria, bronchospasm, hypotension and collapse), muscle cramps, tachycardia develop.
Inhalation drugs can cause paradoxical bronchospasm.Paradoxical bronchospasm should be stopped immediately with another dosage form of salbutamol or another fast-acting inhaled bronchodilator. It is necessary to immediately discontinue the use of the Ventolin inhaler, evaluate the patient's condition, conduct the necessary examination and prescribe appropriate therapy.
Inhalation drugs may cause irritation of the oral mucosa and pharynx.
Therapy with beta2-adrenoreceptor agonists sometimes causes hypokalemia, which can be a serious danger to the patient.
Like other beta2-adrenoreceptor agonists, salbutamol may occasionally cause mental stimulation and increased motor activity in children.
In patients with a predisposition to arrhythmia, salbutamol may cause cardiac arrhythmias, including atrial fibrillation, supraventricular tachycardia, and extrasystole.

special instructions

Patients should be instructed in the proper use of the Ventolin Inhaler.
Bronchodilators should not be the only or main component of the therapy of unstable or severe asthma.
If the effect of the usual dose of Ventolin becomes less effective or less prolonged (the effect of the drug should last at least 3 hours), the patient should consult a doctor.
The increased need for the use of inhaled β2-adrenoreceptor agonists with a short duration of action to control the symptoms of bronchial asthma indicates an exacerbation of the disease. In such cases, the patient’s treatment plan should be reviewed. A sudden and progressive worsening of bronchial asthma can pose a threat to the patient's life, therefore in such situations it is necessary to urgently decide on the appointment or increase in the dose of glucocorticosteroids. In such patients, daily peak expiratory flow rate monitoring is recommended.
Very high doses of salbutamol can lead to the development of adverse reactions, so only a doctor can decide whether to increase the dose or frequency of use of the drug. Patients who use Ventolin Nebula at home need to be warned that if the effect of the usual dose becomes less effective or less prolonged,you can not independently increase the dose or frequency of administration of the drug, and you should immediately consult a doctor.
Ventolin Nebula should be used with caution in patients who have already taken high doses of other sympathomimetics.
Salbutamol should be used with caution in patients with thyrotoxicosis.
Therapy with β2-adrenoreceptor agonists, especially when administered parenterally or with a nebulizer, can lead to hypokalemia. Particular caution is recommended when treating severe attacks of bronchial asthma, since in these cases hypokalemia may be enhanced by the simultaneous use of xanthine derivatives, glucocorticosteroids, diuretics, and also due to hypoxia. In such situations, it is necessary to control the level of potassium in the serum.

Drug interaction

It is not recommended to use salbutamol and non-selective b-adrenoreceptor blockers, such as propranolol, at the same time.
Salbutamol is not contraindicated in patients who receive monoamine oxidase inhibitors (MAOIs).

Overdose

In overdose of salbutamol, the best antidotes are cardioselective b-blockers. However, b-adrenoreceptor blockers should be used with caution in patients with a history of bronchospasm. The use of large doses of salbutamol can cause hypokalemia, therefore, if an overdose is suspected, the level of serum potassium should be monitored.


It is a pharmaceutical drug. Use only as directed by your doctor.

Composition

1 dose contains 100 mcg of salbutamol (in the form of salbutamol sulphate).

Mode of application

Ventolin dosed aerosol is intended only for inhalation.
Only a doctor can decide whether to increase the dose or frequency of the drug.
It is not recommended to use the inhaler Ventolin more often 4 times a day. The need for frequent use of maximum doses of Ventolin or in a sudden increase in dose indicates a worsening course of the disease.
Adults (including elderly patients)
Relief of bronchospasm: the recommended dose is 100-200 mcg (1-2 inhalations).
Prevention of bronchospasm attacks associated with exposure to an allergen or caused by exercise: the recommended dose is 200 mcg (2 inhalations) 10-15 minutes before exposure to the provoking factor.
Long-term maintenance therapy: the recommended dose is up to 200 mcg (2 inhalations) 4 times a day.
Ventolin can be administered via the Volumatik spacer.
Children
Relief of bronchospasm: the recommended dose is 100-200 mcg (1-2 inhalations).
Prevention of bronchospasm attacks associated with exposure to an allergen or caused by exercise: the recommended dose is 100–200 mcg (1-2 inhalations) 10–15 min before exposure to a provoking factor.
Long-term maintenance therapy: the recommended dose is up to 200 mcg (2 inhalations) 4 times a day.
Ventolin can be entered through the 'Babihaler' or 'Volumic' spacer.

Storage conditions
Store at temperatures below 30 ° C.