Amixin pills 125mg 10 pcs.
Trade name of the drug: Amiksin
International non-proprietary name:
2,7-bis- [2 (diethylamino) -ethoxy] -fluorene-9-one dihydrochloride
Dosage form of the drug:
film coated pills
pills, film coated orange, round, biconvex. At the fracture of orange color, slight blotches of orange and white are allowed.
The composition of one tablet
Tiloron - 60 mg or 125 mg.
core: potato starch - 25,500 mg or 46,000 mg, microcrystalline cellulose - 60,000 mg or 120,000 mg, povidone-C30 (collidon 30) - 1,500 mg or 3,000 mg, calcium stearate - 1,500 mg or 3,000 mg, croscarmellose sodium (primeloza) - 1,500 mg or 3,000 mg;
sheath: hypromellose (hydroxypropylmethylcellulose) - 3.4050 mg or 6.8100 mg, titanium dioxide - 1.7815 mg or 3.5630 mg, macrogol-4000 (polyethylene glycol-4000) - 0.4565 mg or 0.9130 mg, polysorbate -80 (tween-80) - 0.0570 mg or 0.1140 mg, the dye quinoline yellow (E 104) - 0.1235 mg or 0.2470 mg, the dye “sunset” yellow (E 110) - 0.1765 mg or 0,3530 mg.
antiviral immunostimulating agent - inducer of interferon formation.
ATC code: J05AH
Low molecular weight synthetic inducer of interferon, which stimulates the formation in the body of interferons of all types (alpha, beta, gamma and lambda). The main producers of interferon in response to the introduction of tilorone are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils and granulocytes. After taking the drug inside the maximum production of interferon is determined in the sequence of the intestine - liver - blood in 4-24 hours. Amiksin has an immunomodulatory and antiviral effect. In human leukocytes, it induces the synthesis of interferon. It also stimulates bone marrow stem cells, enhances antibody production, depending on the dose, reduces the degree of immunosuppression, restores the ratio of T-suppressors and T-helpers. The drug is effective against various viral infections, including influenza viruses and other acute respiratory viral infections, hepatitis viruses and herpes viruses. The mechanism of antiviral action is associated with the inhibition of translation of virus-specific proteins in infected cells, as a result of which reproduction of viruses is suppressed.
After ingestion Amixin is rapidly absorbed from the gastrointestinal tract. Bioavailability - 60%. About 80% of the drug is bound to plasma proteins.The drug is eliminated almost unchanged through the intestines (70%) and through the kidneys (9%). The half-life (T1 / 2) is 48 hours. The drug does not undergo biotransformation and does not accumulate in the body.
Indications for use
Amixin is used in children over 7 years old: for the treatment of influenza and other acute respiratory viral infections.
In adults (over 18):
- treatment and prevention of influenza and other acute respiratory viral infections;
- treatment of viral hepatitis A, B and C;
- treatment of herpes and cytomegalovirus infection;
- as part of the complex therapy of infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, uveoencephalitis, etc.);
- as part of complex therapy of urogenital and respiratory chlamydia;
- In the treatment of pulmonary tuberculosis.
Hypersensitivity to Amiksinu. The period of pregnancy and lactation. Children's age up to 7 years.
Use during pregnancy and during breastfeeding
The use of Amixin during pregnancy is contraindicated. If necessary, the use of the drug during lactation breastfeeding should be discontinued.
Dosage and administration
Amiksin accept inside after food.
For children over 7 years old. With uncomplicated forms of influenza and other acute respiratory viral infections - 60 mg 1 time per day on the 1st, 2nd and 4th day from the start of treatment. Heading dose of the drug - 180 mg (3 pills). If you have complications of influenza or other acute respiratory viral infections - 60 mg 1 time per day on the 1st, 2nd, 4th and 6th day from the start of treatment. Course dose - 240 mg (4 pills).
For adults (over 18 years old). For the treatment of influenza and other acute respiratory viral infections - 125 mg per day for the first 2 days of treatment, then 125 mg after 48 hours. Course dose Amixin - 750 mg (6 pills).
For the prevention of influenza and other acute respiratory viral infections - 125 mg once a week for 6 weeks. Course dose Amixin - 750 mg (6 pills).
For the treatment of herpes, cytomegalovirus infection - the first two days of 125 mg, then after 48 hours of 125 mg. Heading dose - 1.25–2.5 g (10–20 pills).
For non-specific prophylaxis of viral hepatitis A - 125 mg once a week for 6 weeks.
For the treatment of viral hepatitis A - on the first day, 125 mg 2 times, then 125 mg after 48 hours. Course dose Amixin - 1.25 g (10 pills).
For the treatment of acute hepatitis B, the first two days take 125 mg, then 125 mg after 48 hours, for a course of treatment - 2 g (16 pills). With a protracted course of hepatitis B, 125 mg twice a day on the first day, then 125 mg every 48 hours. In the course of treatment - 2.5 g (20 pills).
In chronic hepatitis B - the initial phase of treatment (2.5 g - 20 pills) - the first two days, 125 mg 2 times a day, then 125 mg after 48 hours.The continuation phase (from 1.25 g - 10 pills to 2.5 g - 20 pills) - 125 mg per week. Course dose Amixin - from 3.75 g to 5 g, the duration of therapy - 3.5-6 months, depending on the results of biochemical, immunological, morphological studies, reflecting the degree of activity of the process.
In acute hepatitis C, 125 mg daily for the first 2 days of treatment, then 125 mg after 48 hours. The course of treatment Amiksin - 2.5 g (20 pills).
In chronic hepatitis C - the initial phase of treatment (2.5 g - 20 pills) - the first two days, 125 mg 2 times a day, then 125 mg after 48 hours. The continuation phase (2.5 g - 20 pills) - 125 mg per week. The course dose Amixin - 5 g, the duration of therapy - 6 months depending on the results of biochemical, immunological, morphological markers of the activity of the process.
With the complex therapy of neurovirus infections, 125–250 mg per day for the first 2 days of treatment, then 125 mg every 48 hours. The dose is set individually, the course of treatment is 3-4 weeks.
For urogenital and respiratory chlamydia, the first two days, 125 mg each, then after 48 hours, 125 mg each. Course dose Amixin - 1.25 g (10 pills).
With the complex treatment of pulmonary tuberculosis - 250 mg in the first two days of treatment, then 125 mg in 48 hours. Course dose Amixin - 2.5 g (20 pills).
After using the medication, allergic reactions, dyspeptic symptoms, short-term chills are possible.
Cases of an overdose of Amixin are not known.
Interaction with other drugs
Compatible with antibiotics and drugs traditional treatment of viral and bacterial diseases. Clinically significant interaction of Amixin with antibiotics and traditional treatment of viral and bacterial diseases was not found.
Influence on ability to steer vehicles, mechanisms
Amiksin does not adversely affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and psychomotor reactions.
pills, film coated 60 mg, 125 mg. 6 or 10 pills in a blister pack; 6, 10 or 20 pills in a polymer jar. 1 or 2 blister packs or 1 polymer can together with instructions for Amiksin in a pack of cardboard.
3 years. Do not use Amixin after the expiration date printed on the package.
In the dark place at a temperature of no higher than 30 ° C. Keep Amixin out of the reach of children.
Pharmacy sales terms
Over-the-counter - 125mg film-coated pills. Prescription - 60 mg pills, film coated.
It is a drug. Consultation with a doctor is required.