Alpha-tocopherol acetate (vitamin E) capsules 100mg 10 pcs.

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Alpha-tocopherol acetate (vitamin E) capsules 100mg 10 pcs.

Alpha-Tocopherol Acetate (Vitamin E) Capsules

Vitamin E
(alpha-tocopherol acetate)

Trade name of the drug:

Vitamin E (alpha-tocopherol acetate)

Grouping name:

Vitamin E


Dosage Form: capsules

Composition:

Active substance:

alpha-tocopherol acetate (vitamin E) 100 mg.

Excipients:

sunflower oil 100 mg.

Capsule shell:

gelatin 44.73 mg, glycerol 14.67 mg, methyl parahydroxybenzoate 0.29 mg, dye azorubine 0.31 mg

Description

The capsules are spherical in shape, red, filled with oily liquid from light yellow to dark yellow, without a rancid odor.

Pharmacotherapeutic group

vitamin

Pharmacodynamics

It has antioxidant activity, is involved in the biosynthesis of heme and proteins, cell proliferation, tissue respiration, and other major processes of tissue metabolism; protects tissues from the damaging effects of excess free radicals and peroxide products; stimulates the synthesis of proteins and collagen.

Pharmacokinetics

The absorption from the duodenum (the presence of bile salts, fats, the normal functioning of the pancreas) is necessary - 20-40%. With increasing doses, the degree of absorption decreases. The time to reach maximum concentration is 4 hours. Deposited in all organs and tissues, especially in adipose tissue. Penetrates through the placenta, penetrates into breast milk. Excretion mainly through the gastrointestinal tract, with bile - more than 90%, less than 6% excreted by the kidneys in the form of glucuronides and other metabolites.

Indications for use

Treatment and prevention of vitamin E hypovitaminosis

Contraindications

Increased individual sensitivity to the components of the drug, acute myocardial infarction, children's age.

Carefully

Use in patients with severe cardiosclerosis who have had a myocardial infarction, with an increased risk of developing thromboembolism; hypoprothrombinemia caused by vitamin K deficiency

Use during pregnancy, during lactation

During pregnancy and breastfeeding, taking the drug only on the recommendation of a doctor.

Dosage and administration

The drug is intended only for admission by adult patients.
2 - 4 capsules per day, for 1 - 2 weeks.

Side effect

Allergic reactions (itching, skin flushing); from the gastrointestinal tract: diarrhea, nausea, gastralgia, dyspepsia.

Overdose

When taking vitamin E for a long period in doses of 400-800 IU / day: blurred vision, dizziness, headache, nausea, fatigue, diarrhea, gastralgia, asthenia.


When taking more than 800 IU / day for a long period - an increase in the risk of bleeding in patients with vitamin K vitamin deficiency, metabolic disorders of thyroid hormones, sexual dysfunction, thrombophlebitis, thromboembolism, necrotic colitis, sepsis, renal failure, retinal hemorrhage, hemorrhagic stroke, ascites.


Treatment: symptomatic; drug withdrawal; the appointment of glucocorticosteroids, accelerating the metabolism of vitamin E in the liver.

Interaction with other drugs

The simultaneous intake of large doses of vitamin E with vitamin K or with indirect anticoagulants (coumarin and indandion derivatives) increases the clotting time. Vitamin E enhances the effect of glucocorticosteroids, nonsteroidal anti-inflammatory drugs, cardiac glycosides. When taken concurrently with other vitamin-mineral preparations containing fat-soluble vitamins A, D and E, you should consult your doctor.

Influence on ability to driving of vehicles and control of mechanisms

Taking the drug does not affect the ability of the person to drive vehicles or mechanisms.

special instructions

Do not exceed the recommended dosage. You should not take a double dose if you missed the previous dose.

Storage conditions

In a dry, dark place at a temperature not higher than 25 ° C.
Keep out of the reach of children.

Shelf life
3 years. Do not use after the expiration date.

Pharmacy sales terms
Over the counter.



It is a drug. Consultation with a doctor is required.